Evidence & Trials

Backed By Research

Our team of Experts have worked hard to formulate an effective thermogenic blend using the most innovative technology available to deliver a product that we can be sure of will have a huge impact.

The key ingredients in Metaburn have been carefully selected and combined for their scientifically validated efficacy in aiding weight loss through acceleration of the body's natural fat burning mechanisms.


  • We have used the exclusive new fat burning citrus extract, Sinetrol®, which has been shown to effectively aid weight loss in two scientific studies.

  • Sinetrol® is a patented synergetic blend of active polyphenolic compounds as flavonoids(naringin, nariturin, hesperidin) and anthocyanins (cyanidin-3-glycoside) from unique Mediterranean citrus selected species: Orange, Red Orange and Grapefruit.

  • Sinetrol® acts as a fat burner stimulating the release offree fatty acids (FFA) from the adipocytes. Sinetrol®inhibits the activity of the phosphodiesterase (PDE) which increases the catabolism of triglycerides from the adipocytes. These triglycerides are then released inthe plasma as free fatty acids and glycerol and thenburnt by the energetic metabolism.

  • In the first study involved 10 people in the test group who were given 1.4g of Sinetrol per day and 10 people in thecontrol group who were given a placebo (no Sinetrol) for12 weeks. The graph below shows that there was astatistically significant (p<0.05) decrease in body weightand body fat in the group who took Sinetrol compared to those who took the placebo.

  • In the second study, 95 overweight individuals were given either a placebo or 0.9g Sinetrol per day over a 12 week test period. The results of the study published in the graph below show that there was a significant (p<0.0001) decrease in abdominal body fat (-9.73%), waist size (-5.15cm) and hip size (-5.17cm) compared to people who took placebo.

  • Crucially, it was found that Sinetrol caused the breakdown and mobilisation of fat which was evident as plasma free fatty acid concentration 10 times higher in the Sinetrol group compared to the placebo group. This strong evidence clearly supports the powerful lipolytic effect of Sinetrol.

Amplified By Natural Ingredients

Metaburn combines this pioneering new potent ingredient with Green Coffee BeanExtract, Raspberry Ketones and Green Tea Extract to formulate the most comprehensive thermogenic blend available.

The active ingredient in Green Coffee Bean Extract is chlorogenic acid which functions to slow down the absorption of glucose into the bloodstream after a meal and thereby stimulates utilization of stored fat. Results from studies have confirmed the fatburning properties of Green Coffee Bean Extract; the percentage body fat reduced by 4.4% over a 22 week period of use.

Raspberry Ketones are extracted from a range of superberries including raspberries,blackberries and cranberries and have been shown to be most effective alongside exercise to boost metabolism and fat mobilisation to aid weight loss.

The Green Tea Extract in MetaburnTM contains 90% Polyphenols, making it a potent concentrated source of the active ingredient. It helps to detoxify the body which enables efficient energy use and boosts metabolism to amplify weight loss.


  • Chromium contributes to the maintenance of normal blood glucose levels

  • Thiamine (Vitamin B1) contributes to the normal function of the heart

  • Linoleic acid contributes to the maintenance of normal blood cholesterol concentrations

  • Biotin contributes to normal release of energy for use in the body

  • Vitamin B12 contributes to the normal functioning of the nervous system and helps to reduce tiredness and fatigue

The European Food Safety Authority (EFSA) is the regulatory body of the European Union that serves as an independent agency to review scientific research to provide advice and communication on nutritional ingredients.

EFSA approved products give legal clarity to nutritional ingredients and gives consumers confidence in claims being rigorously assessed and proved to have the stated effects.